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Коллектив авторов |
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Analgesic activity of a natural peptide capable of specific binding to purinergic (P2x3) receptors
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01.01.2018 |
Palikova Y.
Zharmukhamedova T.
Palikov V.
Khokhlova O.
Osipova G.
Andreev Y.
Logashina Y.
Kozlov S.
Yavorskii A.
Murashev A.
D'Yachenko I.
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Eksperimental'naya i Klinicheskaya Farmakologiya |
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0 |
Ссылка
© 2018 Izdatel'stvo Meditsina. All rights reserved. Results of investigation of the analgesic activity of the natural recombinant peptide PT1, which specifically binds to P2X3 receptors, are presented. The test for hypersensitivity provoked by complete Freund's adjuvant (CFA) showed evidence of the analgesic activity of PT1 peptide in CD-I mice after single intravenous administration in a dose range of 0.01-1 mg/kg.
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