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| Название |
Дата публикации |
Коллектив авторов |
Журнал |
DOI |
Индекс цитирования |
Ссылка на источник |
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Reinforced Hybrid Collagen Sponges for Tissue Engineering
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01.05.2018 |
Bardakova K.
Grebenik E.
Istranova E.
Istranov L.
Gerasimov Y.
Grosheva A.
Zharikova T.
Minaev N.
Shavkuta B.
Dudova D.
Kostyuk S.
Vorob’eva N.
Bagratashvili V.
Timashev P.
Chailakhyan R.
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Bulletin of Experimental Biology and Medicine |
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2 |
Ссылка
© 2018, Springer Science+Business Media, LLC, part of Springer Nature. We created an anisotropic material based on collagen sponge and reactive polylactide structured by laser photopolymerization. The combination of collagen with reactive polylactide improves the resistance of the formed matrices to biodegradation in comparison with collagen sponge, while the existence of sites with different mechanical characteristics and cell affinity on the matrix provides directed cell growth during their culturing. It was shown that reinforcement of the collagen sponges 7-fold increased the mean Young’s modulus for the hybrid matrix without affecting its cytotoxicity. The developed matrix provides cell adhesion and proliferation along reinforcement lines and can be used for fabrication of tissue engineering constructs.
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Role of mesenchymal multipotent stromal cells in remodeling of bone defects
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01.01.2018 |
Kiselevsky M.
Anisimova N.
Dolzhikova Y.
Vlasenko R.
Senatov F.
Karaulov A.
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Medical Immunology (Russia) |
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0 |
Ссылка
© 2018, SPb RAACI. Ability of mesenchymal multipotent stromal cells (MSCs) to differentiate into several types of mesenchymal tissues allows to consider these cells the main candidates for creating tissue engineering constructions for regenerative medicine. MSCs promote integration of bio-implants into the native bone and stimulate osteogenesis. MSCs are characterized by immunomodulatory properties, due to inflammation control and modification of immune cells. MSCs affect not only the in vivo immune response by preventing immunological rejection of implanted tissue engineering designs, but it can also influence the bone tissue immunity. MSCs play an important role in bone regeneration, by regulating the osteoblastic generation, and suppressing activity of inflammation effectors and osteoclastogenesis. Some pre-clinical and first clinical trials of bone bio-implants colonized with MSC, demonstrate promising outlooks for this strategy in order to obtain tissue engineering constructions for bone regeneration.
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Human umbilical cord tissue cryopreservation: Prospects for clinical application
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01.01.2018 |
Strokova S.
Arutyunyan I.
Mullabaeva S.
Fatkhudinov T.
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Akusherstvo i Ginekologiya (Russian Federation) |
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0 |
Ссылка
© Bionika Media Ltd. The paper analyzes the data available in the modern scientific literature on the possibility of human umbilical cord tissue cryopreservation and its further clinical application. It describes protocols to obtain various biomedical products (vascular matrix, Wharton jelly-based grafts, and multipotent stromal cells) from the frozen umbilical cord, as well as prospects of their clinical use. The analysis of the literature data may be indicative of the active development of a promising cell biotechnology area, such as human umbilical cord cryopreservation.
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