Репозиторий Университета

Год публикации: Все года 2018 2019 2020

Название	Дата публикации	Коллектив авторов	Журнал	DOI	Индекс цитирования	Ссылка на источник
Novel Solid Dispersions Increasing the Solubility of Prothionamide Polyethyleneglycol-1500(PEG) Polyvinylpyrrolidone-10000(PVP) Prothionamide Soliddispersions Solubility β-Cyclodextrin	01.12.2019	Krasnyuk I. Beliatskaya A. Krasnyuk I. Stepanova O. Galkina I. Lutsenko S. Litvinova T.	BioNanoScience	10.1007/s12668-019-00659-3	0	Ссылка © 2019, Springer Science+Business Media, LLC, part of Springer Nature. Water solubility of prothionamide and its solid dispersions with polyethylene glycol-1500, polyvinylpyrrolidone-10000, and β-cyclodextrin was studied. The most promising results were obtained with the solid dispersion with polyvinylpyrrolidone, which provided a 2.6-fold general increase of drug’s solubility and about a 6-fold dissolution rate increase, the maximal values among the studied drug forms. The results of complex physicochemical studies suggested that the improved drug release was due to micronization and solubilizing action of the polymer. A principal factor was the destruction of the crystal lattice and formation of amorphous particles in the solid dispersion. The obtained data can be useful for the development of modified pharmaceutical forms of prothionamide with improved drug release profile. Читать тезис
Electrically conductive composites of collagen and graphene collagen compositematerials graphene polyvinylpyrrolidone	01.07.2018	Kholkhoev B. Buinov A. Makotchenko V. Fedorov V. Timashev P. Burdukovskii V.	Russian Chemical Bulletin		0	Ссылка © 2018, Springer Science+Business Media, LLC, part of Springer Nature. New composite materials of collagen with electrical conductivity up to 6.1•10 –4 S cm –1 were obtained using colloidal dispersions of polyvinylpyrrolidone-stabilized graphene. Читать тезис

Репозиторий Университета

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